Transdermal Tulobuterol Patch, a Long-Acting β2-Agonist
نویسندگان
چکیده
منابع مشابه
The long-acting β2-adrenoceptor agonist olodaterol attenuates pulmonary inflammation
BACKGROUND AND PURPOSE β2 -adrenoceptor agonists are widely used in the management of obstructive airway diseases. Besides their bronchodilatory effect, several studies suggest inhibitory effects on various aspects of inflammation. The aim of our study was to determine the efficacy of the long-acting β2 -adrenoceptor agonist olodaterol to inhibit pulmonary inflammation and to elucidate mechanis...
متن کاملβ2-Adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting β2-agonist therapy
The aim of the present study was to investigate bronchoprotective sensitivity in patients receiving regular treatment with shortand long-acting β2-agonists and to evaluate any possible association with genetic polymorphism. Thirty-eight patients with stable mild to moderate asthma and receiving inhaled corticosteroids were randomized in a parallel group, double-blind, double-dummy fashion to re...
متن کاملLong-term Safety and Efficacy of Indacaterol, a Long-Acting β2-Agonist, in Subjects With COPD
a From the Asthma and Airway Centre, University Health Network, Toronto Western Hospital, Toronto, ON, Canada b Department of Medicine, University of Toronto, Toronto, ON, Canada c Department of Pulmonary Critical Care, Allergy and Sleep Medicine, University of Nebraska Medical Center, Omaha, NE d Novartis Horsham Research Centre, Horsham, West Sussex, England e Novartis Pharmaceuticals, East H...
متن کاملEffect of β2 -adrenergic receptor gene Arg16Gly polymorphisms on response to long-acting β2-agonist in Chinese Han asthmatic patients
BACKGROUND To evaluate the effect of variation of the Arg16Gly polymorphism of the β2-adrenergic receptor gene on clinical response to salmeterol administered with fluticasone propionate in Chinese Han asthmatic patients. METHODS Moderate persistent asthmatic patients (n = 62) currently receiving short-acting β2-agonists were administered twice-daily therapy with salmeterol/fluticasone propio...
متن کاملEffect of β2-adrenergic receptor gene (ADRB2) 3′ untranslated region polymorphisms on inhaled corticosteroid/long-acting β2-adrenergic agonist response
BACKGROUND Evidence suggests that variation in the length of the poly-C repeat in the 3' untranslated region (3'UTR) of the β2-adrenergic receptor gene (ADRB2) may contribute to interindividual variation in β-agonist response. However, methodology in previous studies limited the assessment of the effect of sequence variation in the context of poly-C repeat length. The objectives of this study w...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2012
ISSN: 1323-8930
DOI: 10.2332/allergolint.11-ra-0358